{"id":9531,"date":"2023-02-15T14:12:35","date_gmt":"2023-02-15T14:12:35","guid":{"rendered":"https:\/\/nanoemulsions.hr\/2023\/02\/15\/is-cbd-safe\/"},"modified":"2023-03-06T19:45:51","modified_gmt":"2023-03-06T19:45:51","slug":"is-cbd-safe","status":"publish","type":"post","link":"https:\/\/nanoemulsions.hr\/en\/2023\/02\/15\/is-cbd-safe\/","title":{"rendered":"Is CBD safe?"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"9531\" class=\"elementor elementor-9531 elementor-9221\">\n\t\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-4989ef7 elementor-section-boxed elementor-section-height-default elementor-section-height-default qodef-elementor-content-no\" data-id=\"4989ef7\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-913ad91\" data-id=\"913ad91\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-6488911 elementor-widget elementor-widget-text-editor\" data-id=\"6488911\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.13.3 - 28-05-2023 *\/\n.elementor-widget-text-editor.elementor-drop-cap-view-stacked .elementor-drop-cap{background-color:#69727d;color:#fff}.elementor-widget-text-editor.elementor-drop-cap-view-framed .elementor-drop-cap{color:#69727d;border:3px solid;background-color:transparent}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap{margin-top:8px}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap-letter{width:1em;height:1em}.elementor-widget-text-editor .elementor-drop-cap{float:left;text-align:center;line-height:1;font-size:50px}.elementor-widget-text-editor .elementor-drop-cap-letter{display:inline-block}<\/style>\t\t\t\t<p><span style=\"font-weight: 400;\">The latest \u201cEuropean Drug Report 2022: Trends and Developments\u201d says:<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cIn 2020, the European Court of Justice published a judgement stating that CBD extracted from the whole hemp plant does not qualify as a narcotic drug, since according to the current scientific understanding the aforementioned plant has no psychoactive properties\u201d.<\/span><\/p>\n<\/p>\n<p><span style=\"font-weight: 400;\">At its November 2017 meeting, the WHO Expert Committee on Drug Dependence (ECDD) concluded that, in its pure state, cannabidiol does not appear to have abuse potential or cause harm.<\/span><\/p>\n<\/p>\n<p><span style=\"font-weight: 400;\">Conclusions of the WHO Expert Committee in 2018: (<\/span> <a href=\"https:\/\/www.who.int\/docs\/default-source\/controlled-substances\/whocbdreportmay2018-2.pdf?sfvrsn=f78db177_2\"><span style=\"font-weight: 400;\">https:\/\/www.who.int\/docs\/default-source\/controlled-substances\/whocbdreportmay2018-2.pdf?sfvrsn=f78db177_2<\/span><\/a> <span style=\"font-weight: 400;\">)<\/span><\/p>\n<\/p>\n<ul>\n<li><span style=\"font-weight: 400;\"> CBD exhibits no effects indicative of abuse or dependence potential in humans<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> CBD has proved to be effective in treating epilepsy; prescription medicine called Epidiolex\u00ae is about to be approved in the USA (Note: it was later approved on June 26, 2018)<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> preliminary preclinical evidence suggests that CBD may be useful in treating a number of other medical conditions<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> medicinal use of CBD products is not regulated, but also not prohibited<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> CBD is generally well-tolerated with a good safety profile<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Furthermore, according to the aforementioned Conclusions, there is evidence of effectiveness of CBD in treating not only epilepsy, but numerous other medical conditions as well. Less comprehensive research studies show preclinical evidence, while others also include a combination of preclinical and clinical evidence on neuroprotective, antiepileptic, hypoxic-ischemic, anxiolytic, antipsychotic, analgetic, anti-inflammatory, anti-asthmatic and anti-cancer properties of CBD.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The latest human clinical trials indicate a therapeutic role of CBD in transplantation.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Other possible therapeutic uses include drug addiction. A limited number of preclinical studies suggests CBD\u2019s therapeutic effect in opioid, cocaine and psychostimulants, marijuana with a high THC percentage, and tobacco addiction.<\/span><\/p>\n<\/p>\n<p><span style=\"font-weight: 400;\">It is necessary to emphasize the importance of a significantly broader and more comprehensive research on the therapeutic use of CBD, especially because it has been observed that CBD is more effective if used in synergy with other active ingredients of cannabis (<\/span><i><span style=\"font-weight: 400;\">cannabinoids<\/span><\/i><i><span style=\"font-weight: 400;\">,<\/span><\/i> <i><span style=\"font-weight: 400;\">terpenes<\/span><\/i> <i><span style=\"font-weight: 400;\">and<\/span><\/i> <i><span style=\"font-weight: 400;\">flavonoids<\/span><\/i>)<span style=\"font-weight: 400;\">, which opens the possibility for a much broader research area.<\/span><\/p>\n<\/p>\n<p><span style=\"font-weight: 400;\">Due to its beneficial effects and mild and unharmful side-effects, many pharmaceutical companies use CBD in the development of their products. Here are some of them:<\/span><\/p>\n<\/p>\n<ul>\n<li><span style=\"font-weight: 400;\"> GW Pharmaceuticals (Great Britain)<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> Echo Pharmaceuticals (The Netherlands)<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> Zynerba\u00ae Pharmaceuticals (USA)<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> Bionorica\u00ae (Germany)<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> STI Pharmaceuticals (Great Britain)<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> INSYS Pharmaceuticals (USA)<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> PhytoTech Therapeutics (Tel Aviv, Israel)<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> Ananda Scientific (Israel)<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> GW Pharmaceuticals (USA)<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">Regarding the side-effects, it is useful to emphasise the advantages of full-spectrum oils over CBD isolate. An article (<\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7558665\/\"><span style=\"font-weight: 400;\">https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7558665\/<\/span><\/a><span style=\"font-weight: 400;\"> ) published on PMC states that mild side-effects were 2.5 times less frequent in patients who used full-spectrum oils in comparison to those who used CBD isolate. However, seen that the dose of CBD in the isolate was considerably higher than the one in full-spectrum CBD oil, it remains unclear whether the smaller number of side-effects was caused by a lower dosage or by the use of the full-spectrum oil. The aforementioned research also showed that there were no apparent differences in the effectiveness of higher doses used in CBD isolate in comparison to full-spectrum CBD oil. From this it follows logically that it is far better to use full-spectrum CBD oil than CBD isolate. Not only is the possibility of mild side-effects considerably lower, but it is also more economical as smaller quantities have the same effect.<\/span><\/p>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>The latest \u201cEuropean Drug Report 2022: Trends and Developments\u201d says:<\/p>\n<p>\u201cIn 2020, the European Court of Justice published a judgement stating that CBD extracted from the whole hemp plant does not qualify as a narcotic drug, since according to the current scientific understanding the aforementioned plant has no psychoactive properties\u201d.<\/p>\n","protected":false},"author":1,"featured_media":9379,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[115],"tags":[],"class_list":["post-9531","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-uncategorized-de"],"_links":{"self":[{"href":"https:\/\/nanoemulsions.hr\/en\/wp-json\/wp\/v2\/posts\/9531","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/nanoemulsions.hr\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/nanoemulsions.hr\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/nanoemulsions.hr\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/nanoemulsions.hr\/en\/wp-json\/wp\/v2\/comments?post=9531"}],"version-history":[{"count":5,"href":"https:\/\/nanoemulsions.hr\/en\/wp-json\/wp\/v2\/posts\/9531\/revisions"}],"predecessor-version":[{"id":9657,"href":"https:\/\/nanoemulsions.hr\/en\/wp-json\/wp\/v2\/posts\/9531\/revisions\/9657"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/nanoemulsions.hr\/en\/wp-json\/wp\/v2\/media\/9379"}],"wp:attachment":[{"href":"https:\/\/nanoemulsions.hr\/en\/wp-json\/wp\/v2\/media?parent=9531"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/nanoemulsions.hr\/en\/wp-json\/wp\/v2\/categories?post=9531"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/nanoemulsions.hr\/en\/wp-json\/wp\/v2\/tags?post=9531"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}